Human cryopreservation: the "Everest" of cryonics
Release time:
2023-08-23
Borges, a well-known writer in the 20th century, once said that the essence of human existence is the experience of death over and over again, and "death makes people wise and sad". Therefore, in the history of mankind, people are constantly breaking through themselves, challenging the boundaries of science and technology, the peak of medicine, and the length of human life is constantly extended in the long river of time.
Human cryopreservation is the "Mount Everest" which is being climbed by modern cryogenic medicine researchers, and it is also called "the technology of solidifying time" by many people.
NO.1 Courageous exploration in the spirit of science
British biomedical scientist Aubrey de-Grey once said, "human cryopreservation technology is not a feudal superstition, but a brave attempt based on science". Human cryopreservation is an experimental research naturally derived from the continuous progress of research on cryopreservation technology, which has a certain scientific foundation.
At present, people have successfully realized the cryopreservation and resuscitation of all kinds of stem cells, sperm, oocytes, embryos and some tissues and organs. In Shandong Yinfeng Life Science Research Institute has mastered the deep cryopreservation and resuscitation technology of skin, severed fingers/toes, valves, ovaries, bones, tendons, blood vessels, pancreatic islets, etc., and has successfully implemented the preservation of nearly 200 cases of tissues and organs, and some of them have been resuscitated and replanted successfully.
On the basis of the technology for the preservation of cells, some tissues and organs, it seems to be a watertight process to carry out human cryopreservation. Theoretically, through deep cryopreservation, cells and even organisms can be frozen to extremely low temperatures and then rewarmed in an effective way when needed, and the awakened organisms can still remain active. Because of the low-temperature environment, greatly reduce or even suspend the rate of metabolism of the organism, and at the same time avoid a variety of external interference in the process of long-term preservation, so after the resuscitation of the organism's functions can still be restored as in the beginning, just like a newborn.
Therefore, the human body cryopreservation technology does not only exist in science fiction, it has a certain scientific basis and practical applications. However, it is undeniable that, although the current cryopreservation technology has matured on the cellular scale, it is still difficult to implement for slightly larger tissues or organs, or human body, such as the ice crystal problem in the cooling and the reverse vitrification problem in the rewarming.
Based on the existing technology, Shandong Yinfeng Life Science Research Institute has been continuously conducting research on cryoprotectant and cooling equipment, cryopreservation equipment, perfusion surgical protocols and monitoring systems, etc., and has obtained a number of patents to minimize the formation and growth of ice crystals in the process of human cryopreservation.
NO.2 Coagulation Time, Suspension of Death
If cryopreservation technology can maintain cell viability, then the prerequisite and necessary condition for the implementation of human cryopreservation surgery is that the cells of the patient's body and brain are still "alive".
In China, although the determination of death criteria is striving to be infinitely close to brain death, the occurrence of death is not an instantaneous concept, even if the heart stops beating and breathing stops, the cells of the body and the brain are still "alive" for a long time, which is the last window of time left for life. The process of implementing human cryopreservation is also initiated during this time, in order to interrupt the patient's death and seek new ways to cure the disease.
Therefore, in the eyes of many people, human cryopreservation is an extension of modern emergency medicine. And in the legal sense was pronounced "dead" people, but also seems to be just for life pressed the pause button, is to accept another new type of treatment "patient" only, which is with the final struggle of the disease, but also with the final struggle of death.
NO.3 Difficulties still exist
In the natural world, although there have been many low-temperature experience can still be resurrected phenomenon, such as certain types of moths, North American tree frogs and so on. Russian scientists have also awakened 40,000 years ago frozen nematodes. But there are still huge challenges to the cryopreservation of the human body. For example, how to avoid recrystallization of ice crystals when rewarming, whether the original disease has been cured, etc. We are counting on the future power of science and technology, in the future full of infinite possibilities, all of this may no longer be a problem.
Liu Cixin, a famous science fiction writer in China, called the human hibernation technology in "Three Bodies" as "the first upright walk of mankind in time". Like a toddler, human cryopreservation may be staggering forward, but we believe that with the rapid progress and breakthroughs in medical technology, mankind will eventually walk faster and farther on the track of time.
Latest developments
Over the two days, the symposium was not only a collision of ideas but also seeds sown to advance social progress in life culture. The Shandong Yinfeng Life Science Public Welfare Foundation will continue to use technology as wings and culture as roots, collaborating with all sectors of society to enhance the quality of life for the Chinese people and build a human-centered life care system.
According to recent announcements by the Jinan Municipal Bureau of Science and Technology, 11 outstanding achievements from Jinan have been included in the 2025 "Shandong Outstanding Achievements Report" project. Among them is the globally first-of-its-kind ovarian tissue dual-activation technology developed by Shandong Silver Med Life Science Research Institute (Jinan).
Recently, Frigid Zone Medicine, an authoritative international journal in the field of cryomedicine, published an important review titled "Advances in the Detection Methods for Assessing the Viability of Cryopreserved Samples". Written by the team of Yinfeng Cryomedical Research Center, the article systematically reviews and analyzes various detection techniques currently used to evaluate the viability of cryopreserved cells, tissues, and organs. It also proposes key directions from the perspectives of methodological integration and future instrument development, offering crucial theoretical support and practical guidance for the long - term cryopreservation of complex tissues and organs.
Recently, the "Novel Technology for Ultra-Low Temperature Cryopreservation, Activation, and Transplantation of Human Ovarian Tissue," developed through a collaborative effort between Shandong Yinfeng Life Science Research Institute and Beijing University of Chinese Medicine Shenzhen Hospital, has been awarded the 2025 Shandong Refrigeration and Air Conditioning Science and Technology Award. This groundbreaking technology pioneers a new pathway for female fertility preservation, marking a significant leap in China’s interdisciplinary advancements in reproductive medicine and cryobiology.
On May 19, a delegation from the Chinese Training Workshop for Government Officials of Developing Countries visited the exhibition hall of Yinfeng Biological Group's Cryomedicine Research Center. Government officials from multiple countries gained in-depth insights into Yinfeng’s innovative achievements in cryobiomedicine, cell storage, genetic technology, and other fields. They engaged in discussions with the delegation on technology transfer and international cooperation, contributing to the building of a global community with a shared future for humanity.
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