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Yinfeng Life Extension Plan Q&A


Can healthy people become participants in research on cryopreservation and rewarming techniques for large intact organisms?

Under current Chinese laws and regulations, the program can only be implemented after the clinical death of the volunteer. If you are currently in good health but are deeply interested in this program, you can first apply to become a member of the Yinfeng Life Extension Program.

Can I apply to become a participant if I do not live in Shandong Province?

Yes, it is recommended that volunteers be transferred to a hospital/hospice in Jinan, Shandong for treatment in advance to ensure seamless and smooth implementation of the program. If the participant enters their end-stage outside Jinan, there may be outcomes such as inability to perform transfers and inability to respond clinically in a timely manner.

How can the long-term operation of this program be guaranteed?

Shandong Yinfeng Life Science Research Institute has been approved for the qualification of Volunteer Body-Donating Registration Station, and it is legal and compliant to carry out the research on body resources
The Shandong Yinfeng Life Science Foundation, a government-approved charitable organization, has established a Yinfeng Life Extension Fund to provide long-term and stable financial support for the program. The funds mainly come from Yinfeng Group's self-financing and donations from members of the Yinfeng Life Extension Program.

Do power outages affect participant cryopreservation?

No. Cryopreservation primarily uses liquid nitrogen as a refrigerant, and participants are preserved for long periods of time in a liquid nitrogen environment. Power outages do not affect the preservation temperature.

Are there any cases of animal experiments being cryopreserved and then rewarmed?

There were no cases of rewarming of intact animals to make them revive to date, but the animal experiments are still conducted under our program. Cryopreservation under ultra-low temperature and rewarming at the tissue level of bone/skin/broken fingers/ovarian tissue are already widely used in clinical practice. In 2023, organs rewarming has been achieved, for instance, in June 2023, researchers at the University of Minnesota, USA, have achieved long-term freezing and rewarming of kidneys in rats, which were able to produce urine after transplantation. This is the first time that scientists have demonstrated that mammalian organs can be successfully transplanted and restore function after cryopreservation and rewarming.With the development of emerging technologies such as regenerative medicine/artificial intelligence, more technological pathways will be available for rewarming and functional reconstruction of intact organisms.

How does vitrification cryopreservation technology protect cells?

Vitrification cryopreservation refers to the use of a vitrification cryopreservation solution, composed of high concentrations of cryoprotectants, in an ultra-low temperature environment that increases the viscosity of the solution by strong hydrogenation with water molecules,  forming an irregular glass-like solid that maintains the normal molecular and ionic distribution in the liquid state and reduces the rate of ice crystal formation, thus protecting the cells of the preservation target during the rapid cooling and rewarming process. In 1998, vitrification cryopreservation technology was formally applied to cryonics, showing great potential for research into cryopreservation and rewarming technology for large intact organisms.

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