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World's first! "Pig liver" successfully transplanted into the human body

2024/03/22

On March 10, led by Academician Dou Kefeng of the Chinese Academy of Sciences and Director Tao Kaishan from Hepatological Surgery Department, Xijing Hospital of Air Force Military Medical University made a major breakthrough in the clinical research of liver heterotransplantation: the whole liver of a multi-gene edited pig was successfully transplanted into a brain-dead patient using the auxiliary liver transplantation method. During the operation, the transplanted liver secreted bile immediately after blood flow was restored with no hyperacute rejection, and functioned continuously for more than 96 hours.

Heavyweight! Prof. Gang Zhao, the main committee member of Yinfeng Cryomedicine Specialized Committee, published another article "Advanced Cryopreservation Engineering Strategies - A Critical Step in Utilizing Stem Cell Products".

2023/09/08

Cryopreservation is known as the technique of solidifying time, by cooling biological materials (e.g. cells, tissues and organs) to low temperatures with the addition of cryoprotectants (generally -196°C liquid nitrogen preservation), and then rewarming them to normal temperatures (37°C) in an effective manner when needed, at which time the biological samples can still be restored and maintain their activity.

Heavy! Professor Zhao Gang, chairman of our special committee, jointly published an important article - "Principles and Progress of Cell Cryopreservation"

2023/07/21

In recent years, low-temperature biomedicine, a less popular subject, is attracting more and more attention, attracting more and more scientists to join it. Among them, the cryopreservation technology of cells, tissues and organs, and even the entire human body continues to make progress and is gradually used in clinical applications.

Science's latest cover article: Vital organs resuscitated after cryogenic freezing

2023/07/14

On June 30, 2023, Science Magazine published the article "Frozen in time" by Warren Cornwall, detailing the first successful transplantation of vitrified-preserved and nanoheated rat kidneys by Professor John Bischof's team at the University of Minnesota (UMN). . As the most exciting research in the field of cryopreservation of tissues and organs, this article successfully appeared on the cover of Science, Volume 380, Issue 6652.

2023-11-30

Pig organs transplanted to monkeys, another new advance in cross-species transplantation

Multiple organs and tissues, including liver, kidney, heart, abdominal wall, cornea, bone, median nerve, etc., from a gene-edited pig were transplanted to seven recipient monkeys. "The study is another useful exploration and positive attempt to find out whether xenotransplantation of tissues and organs is feasible to be applied to emergency treatment of severe tissue destruction and organ failure, which will further expand the feasibility and effectiveness of confirming the application of xenotransplantation to medical rescue." At the media conference held on the 10th, Dou Kefeng, an academician of the Chinese Academy of Sciences, gave a high evaluation of the operation.

2023-11-30

Miracle! Man's thumb was severed for 76 hours, successfully resuscitated

Recently, a banner full of patients' gratitude was sent to the hands of hand and foot surgeons of Qilu Hospital. It turned out that, just more than twenty days ago, Mr. Lu's left thumb was cut off by a machine while he was working at a construction site. The incident was sudden, and the severed finger could not be found during the emergency medical treatment. Two days later, the possibility of being separated from the broken finger and then pick up the living is minimal.

2023-09-08

Heavyweight! Prof. Gang Zhao, the main committee member of Yinfeng Cryomedicine Specialized Committee, published another article "Advanced Cryopreservation Engineering Strategies - A Critical Step in Utilizing Stem Cell Products".

Cryopreservation is known as the technique of solidifying time, by cooling biological materials (e.g. cells, tissues and organs) to low temperatures with the addition of cryoprotectants (generally -196°C liquid nitrogen preservation), and then rewarming them to normal temperatures (37°C) in an effective manner when needed, at which time the biological samples can still be restored and maintain their activity.

2023-09-01

Breaking! U.S. transplants pig kidneys to humans, now surviving for over a month

As we all know, organ transplantation, as the last resort treatment for many end-stage organ diseases, has long been in an objective situation where demand far exceeds supply (organ donation). As a result, many research teams have also put their hopes for a breakthrough in the field of xenotransplantation - trying to make pig hearts, pig kidneys and pig livers work in the human body.

2023-08-25

Spinal cord-like tissue transplantation helps paralyzed rats regain motor function

Dai Jianwu, a researcher at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (IGDB, CAS), and Yannan Zhao, a young researcher, have made a new progress in the study of in vitro fabrication of human spinal cord tissues, which, when transplanted, help to restore motor functions in paralyzed rats. The related study was recently published in Science Advances.

2023-08-25

The real-life version of "Avatar" is here! Scientists create human organs with chips

In medical research laboratories, we often see small animals such as mice, rabbits or frogs, which are used as animal models to become experimental, drug-testing or even anatomical objects, and make great sacrifices for human medical research.

2023-08-23

Going beyond sci-fi: the human 4S store that makes organ repair possible

When the car traveled to a certain mileage, we need to go to the 4S store to do maintenance to the car, so as to keep the car in a safe state of use. In fact, people and cars are similar, the human body in the process of operation also need maintenance, regenerative medicine "human 4S store", through advanced regenerative medicine technology, to achieve the goal of "where the bad repair where".

2023-08-23

Human cryopreservation: the "Everest" of cryonics

Borges, a well-known writer in the 20th century, once said that the essence of human existence is the experience of death over and over again, and "death makes people wise and sad". Therefore, in the history of mankind, people are constantly breaking through themselves, challenging the boundaries of science and technology, the peak of medicine, and the length of human life is constantly extended in the long river of time.

2023-08-18

New Breakthroughs! New explorations in skin cryopreservation to help new advances in cryogenic research

The human body is an organic organism composed of cells and complex tissues and organs. When the tissues and organs in the body are damaged or lose their original functions, tissue and organ transplantation can replace the damaged or dysfunctional parts by implanting a part of the tissues and organs from the own body or other individuals.