Science Outreach-YINFENG LIFE EXTENSION PROGRAM

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Breakthrough Organ Preservation Technology: Achieving Long-Term and Safe Preservation of Cells and Organs

Breaking the Cryopreservation Bottleneck: New Pretreatment Technique Boosts NK Cell Recovery Rate to 90%–100% After Thawing

Scientists Achieve Functional "Revival" of Mouse Brain Tissue After Rewarming from -196°C Freezing First Successful Revival of Frozen Brain! Mouse brain tissue regains memory function after being frozen at -196°C and rewarmed

Good News! Three Organoid Cryopreservation Technologies of Our Team Accepted for National Patents

The World's First In - Vitro Dual Activation Technology for Primitive Follicles: A Baby Born after Intra - operative Ovarian Tissue Freeze - Thaw Transplantation

Significant Achievements: Successfully Cultivated Human Heart in Pigs, Bringing New Hope for Organ Transplantation

Breakthrough Organ Preservation Technology: Achieving Long-Term and Safe Preservation of Cells and Organs

2026/05/18

Beyond organ transplantation, this non-toxic low-temperature preservation framework can be extended to long-term storage of stem cells, reproductive cells, and germplasm resources of endangered species, providing a universal technological foundation for biobanks, regenerative medicine, and other fields.

Breaking the Cryopreservation Bottleneck: New Pretreatment Technique Boosts NK Cell Recovery Rate to 90%–100% After Thawing

2026/04/29

The clinical value of this approach lies in its extremely simple operation. It requires no specialized cryopreservation solutions or complex equipment, using only GMP‑grade compliant cytokines that can be removed by routine washing after pretreatment, posing no additional safety risks to patients and enabling rapid integration into existing cell production and cryopreservation workflows. As the large‑scale manufacturing of NK cells derived from umbilical cord blood and iPSCs becomes increasingly mature, combining this cryopreservation technology holds the potential to significantly reduce cell therapy costs and improve accessibility, opening new avenues for immunotherapy in hematological malignancies and solid tumors.

Scientists Achieve Functional "Revival" of Mouse Brain Tissue After Rewarming from -196°C Freezing First Successful Revival of Frozen Brain! Mouse brain tissue regains memory function after being frozen at -196°C and rewarmed

2026/03/16

In science fiction, human cryopreservation and resuscitation are often regarded as a "time capsule" to the future. Now, this concept has achieved a milestone breakthrough in the laboratory—scientists have for the first time successfully cryopreserved adult mouse brain slices in liquid nitrogen at -196°C and restored multiple key neural functions, including learning and memory mechanisms, after rewarming. This achievement blazes a brand-new trail for basic neuroscience research and organ preservation technology.

Good News! Three Organoid Cryopreservation Technologies of Our Team Accepted for National Patents

2025/08/15

In the era of rapid development of organoid research, achieving long - term stable preservation while maintaining biological activity and functional integrity remains a crucial bottleneck restricting the clinical translation of this technology and its application in drug R & D. Recently, three technological inventions by the research team of Yinfeng Low - Temperature Medical Research Center were accepted by the National Intellectual Property Administration. These three technologies focus on the challenges of organoid cryopreservation and cover the key steps in the entire process of organoid vitrification preservation, offering a more efficient and reliable solution for safeguarding biological samples in organoid research.

The World's First In - Vitro Dual Activation Technology for Primitive Follicles: A Baby Born after Intra - operative Ovarian Tissue Freeze - Thaw Transplantation

2025/07/03

On June 25, 2025, the team led by Professor Wang Huiying and Dr. Jin Bo from Shenzhen Hospital of Beijing University of Chinese Medicine collaborated with Shandong Yinfeng Life Science Research Institute to develop the "ovarian dual activation" technology. Through this technology, patients with POI (primary ovarian insufficiency) underwent intra - operative freeze - thaw activation of ovarian tissue. After intra - operative transplantation, a baby was born, and both the mother and the baby are healthy and safe.

Significant Achievements: Successfully Cultivated Human Heart in Pigs, Bringing New Hope for Organ Transplantation

2025/06/19

Recently, the world's top - tier academic journal Nature featured a major research achievement by Chinese scientists on its front - page headlines. For the first time, a heart containing human cells was cultivated in a pig embryo, and this heart could beat autonomously and survived for 21 days. This groundbreaking progress offers a brand - new solution to the global shortage of organ transplants and marks a new stage in the development of xenogeneic organ cultivation technology.

2026-07-10

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Lab-Grown "Potato Cells": A Milestone in Building Life from Scratch

From "simulating life" to "creating it," humanity has journeyed for decades. SpudCell may not be the final destination, but the spark it ignites is illuminating a new path for synthetic biology toward real-world utility.

2026-07-10

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Healing Without Snipping DNA: Epigenetic Editing Opens a New Frontier in Gene Therapy

This "revolution without scissors" is nevertheless opening up vast new possibilities for the future of gene therapy.

2026-06-26

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Cover Story | Solving the Challenge of Deep Hypothermic Brain Protection: Unveiling a Novel Mechanism of White Matter Injury

This study not only fills a critical mechanistic gap in the field of hypothermic brain protection but also provides precise therapeutic targets for the prevention and treatment of white matter injury after complex congenital heart surgery.

2026-06-26

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《Science》: Hyaluronic Acid and Tissue Mechanics Synergistically Regulate Mammalian Digit Tip Regeneration

This work was completed by scholars including Mui, Wong, and Storer from the University of Cambridge. In the same issue, Science also published a related study on oxygen-sensing regulation of limb regeneration, collectively providing important breakthroughs in understanding the mechanisms of mammalian regeneration.

2026-06-22

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Novel Strategy for Cell Cryopreservation: Pre-Dehydration via Droplet Vacuum Evaporation

This approach holds broad application prospects in regenerative medicine (e.g., stem cell transplantation and organoid transplantation), drug screening (preservation of high‑throughput cell models), and biobanking (long‑term storage of rare cell resources).

2026-06-22

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Cell Cover: Atlas of Human Cellular Senescence Unveiled, Ushering in the Era of Precision Anti-Aging

Professor Rong Fan, Executive Director of the SenNet consortium, remarked: “This atlas allows us, for the first time, to see the true distribution and diversity of senescent cells within the human body.” The consortium has made all data openly accessible at https://data.sennetconsortium.org for researchers worldwide. Industry experts believe this achievement will shift the medical paradigm from “treating disease after onset” to “pre‑identifying and eliminating harmful senescent cells,” with promising breakthroughs expected in neurodegenerative diseases, fibrotic liver disease, chronic wounds, and metabolic syndrome.

2026-06-12

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World’s First “Reverse Aging” Gene Therapy Completes First Human Injection

In addition to eye diseases, Life Biosciences is exploring the potential of “partial reprogramming” for conditions such as liver fibrosis. If this trial confirms its safety and feasibility, it could open an entirely new path for anti-aging medicine—shifting from passively managing age-related diseases to actively reversing the aging process at the cellular level.

2026-06-12

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Blocking "Xenophagocytosis": A Key Step Toward Growing Human Organs in Animals

Experts in the field believe that this study has found the key to protecting cross-species cells from early immune system clearance, opening a new door for regenerative medicine.

2026-06-05

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"Cell Robots": Magnetic Remote-Controlled Stem Cells Promote Spinal Cord Regeneration

To move toward clinical application, the team is developing a multi-chip parallel system to boost production capacity, with potential future expansion into areas such as cardiovascular disease, tumor therapy, and wound healing. From spinal cord repair to other hard-to-treat diseases, this technology may bring new hope to countless patients.

2026-06-05

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World’s First! Chinese Team Successfully Achieves Combined Whole Liver and Dual Kidney Xenotransplantation in a Human

Millions of people worldwide lose their lives each year due to organ shortages. This breakthrough proves that multi‑organ xenotransplantation is feasible in the complex human environment, and the Chinese team is illuminating a new dawn for the organ shortage crisis.