New Breakthrough! This Household Medicine Can Reset the "Aging Clock" in Primates
Release time:
2024-09-23
A major discovery! The team led by Liu Guanghui from the Chinese Academy of Sciences, in collaboration with top-tier researchers, has published a groundbreaking paper in the journal Cell, revealing the novel anti-aging effects of metformin—a "veteran drug."
After eight years of intensive research, scientists have for the first time mapped out an anti-aging blueprint for primates, demonstrating that metformin not only controls blood sugar but also decelerates the aging clock.
In a 40-month-long study, they found that metformin can significantly slow down the aging process in male crab-eating macaques. Multiple organs—from brain to heart, liver to bones—exhibited a "youthful" state. This is not just a marginal improvement but a systemic "age-reversal" effect.
What's the secret? Metformin doesn't merely regulate metabolism but activates the cellular antioxidant gene network, directly combating aging. It's like installing a "youth switch" in cells, rejuvenating them.
Notably, the protective effects of metformin on the brain are particularly significant, enhancing cognitive function and fighting neural degeneration. This brings new hope in the battle against age-related diseases like Alzheimer's.
Scientists also used machine learning to construct precise aging assessment models, confirming that metformin could make the "biological age" of primates six years younger—the equivalent of 18 human years! This isn't just a reduction in numbers but a significant leap in life quality!
This groundbreaking discovery not only brings new hope to the field of anti-aging but also provides a clear direction for future anti-aging drug development. Metformin, this old drug with a new application, might just become the "super weapon" against human aging.
Latest developments
Over the two days, the symposium was not only a collision of ideas but also seeds sown to advance social progress in life culture. The Shandong Yinfeng Life Science Public Welfare Foundation will continue to use technology as wings and culture as roots, collaborating with all sectors of society to enhance the quality of life for the Chinese people and build a human-centered life care system.
According to recent announcements by the Jinan Municipal Bureau of Science and Technology, 11 outstanding achievements from Jinan have been included in the 2025 "Shandong Outstanding Achievements Report" project. Among them is the globally first-of-its-kind ovarian tissue dual-activation technology developed by Shandong Silver Med Life Science Research Institute (Jinan).
Recently, Frigid Zone Medicine, an authoritative international journal in the field of cryomedicine, published an important review titled "Advances in the Detection Methods for Assessing the Viability of Cryopreserved Samples". Written by the team of Yinfeng Cryomedical Research Center, the article systematically reviews and analyzes various detection techniques currently used to evaluate the viability of cryopreserved cells, tissues, and organs. It also proposes key directions from the perspectives of methodological integration and future instrument development, offering crucial theoretical support and practical guidance for the long - term cryopreservation of complex tissues and organs.
Recently, the "Novel Technology for Ultra-Low Temperature Cryopreservation, Activation, and Transplantation of Human Ovarian Tissue," developed through a collaborative effort between Shandong Yinfeng Life Science Research Institute and Beijing University of Chinese Medicine Shenzhen Hospital, has been awarded the 2025 Shandong Refrigeration and Air Conditioning Science and Technology Award. This groundbreaking technology pioneers a new pathway for female fertility preservation, marking a significant leap in China’s interdisciplinary advancements in reproductive medicine and cryobiology.
On May 19, a delegation from the Chinese Training Workshop for Government Officials of Developing Countries visited the exhibition hall of Yinfeng Biological Group's Cryomedicine Research Center. Government officials from multiple countries gained in-depth insights into Yinfeng’s innovative achievements in cryobiomedicine, cell storage, genetic technology, and other fields. They engaged in discussions with the delegation on technology transfer and international cooperation, contributing to the building of a global community with a shared future for humanity.
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