Major Breakthrough in Artificial Liver Research
Release time:
2024-07-30
Recently, the liver surgery team at Peking Union Medical College Hospital, in collaboration with several research institutions, has achieved a significant breakthrough in the field of artificial liver research. The research team successfully constructed a novel artificial liver with hepatic vein structures (HEALs) and a liver tissue model with enhanced activity and functional advantages using suspension printing technology and holographic lattice acoustic tweezer technology. This provides a new potential pathway for liver transplant alternatives, making tissue engineering technologies faster and more efficient. The related research findings have been published in the journal "Biomaterials."
One significant achievement of this study is the successful printing of HEALs with venous structures based on a "omnidirectional suspended printing matrix network" supporting medium. Compared to traditional 3D printed livers, HEALs not only achieve centimeter-level tissue construction but also show significant advantages in liver function expression and vascular regeneration after transplantation, making them promising for drug screening, basic research, and liver transplant replacements.
Another important achievement is the collaboration with other research institutions to optimize and utilize holographic lattice acoustic tweezer technology to construct an in vitro biomimetic 3D liver model. Primary hepatocytes subjected to holographic lattice acoustic tweezers can generate a large number of self-assembling hepatocyte spheroids within one minute. The speed is fast, and after in vitro culture, the diameters of the hepatocyte spheroids significantly increase, with substantial enhancements in core functions such as protein synthesis metabolism, glucose metabolism, and detoxification.
The research team stated that the holographic lattice acoustic tweezer technology, with its unique advantages of being non-contact, non-damaging, precise, flexible, and rapid in patterning processes, shows great potential in constructing in vitro 3D models.
Previous article
Latest developments
The debut and discourse of the YinFeng Life Continuation Project not only served as an authoritative demonstration of its own ethical governance framework but also contributed practical wisdom toward establishing industry norms.
Yinfeng Foundation Honored as "2025 Public Welfare Donor" by Jinan Red Cross
Looking ahead, Yinfeng Foundation will use this recognition as an opportunity to further deepen its strategic collaboration with the Jinan Red Cross, expand cooperation in areas such as life health and emergency response, and continue to empower efforts to accelerate the construction of a "new, strong, excellent, rich, beautiful, and high-quality" modern socialist strong capital city, contributing even more Yinfeng strength to this endeavor.
The team successfully developed the CryoSIM platform, an intelligent microfluidics and deep learning-integrated system. This platform deeply integrates core technologies of deep learning and microfluidics to enable high-throughput, high-precision automated analysis of oocyte membrane permeability. It provides a novel technological tool for optimizing and advancing the clinical translation of oocyte cryopreservation techniques. Additionally, it offers an innovative practical paradigm for the application of artificial intelligence in low-temperature biomedicine and reproductive medicine.
Public Welfare Partnership: A Special Letter from the Jinan Red Cross
On the afternoon of January 30, 2026, the Jinan Red Cross presented a letter of special significance to the Shandong Yinfeng Life Science Public Welfare Foundation (hereinafter referred to as the Yinfeng Foundation).
World’s First Achievement Highlights Brand Leadership
In the future, Yinfeng Life Science Research Institute will continue to uphold its mission of "Dedicated to Medical Technology, Safeguarding Human Health." It will empower brand building with more original and pioneering scientific and technological achievements, contributing wisdom and strength to Shandong's goal of building a national regional innovation hub and promoting Chinese brands on the global stage.
Global First Ovarian Tissue Dual Activation Technology Debuts at 2025 Jinan Achievements Conference
Currently, the ovarian tissue dual activation technology has been successfully applied in clinical practice at Beijing University of Chinese Medicine Shenzhen (Longgang) Hospital, having treated over 400 patients with a treatment success rate of 70%. Over the next three years, Shandong Yinfeng Life Science Research Institute plans to use Jinan as a center to gradually expand the transformation and application of this technological achievement nationwide.
Yinfeng Life Continuation Plan
Address: Yinfeng Biotechnology Park, 1758 Gangyuan 6th Road, High-tech Zone, Jinan City, Shandong Province
Zip Code: 250102
Telephone: 0086-0531-88897351
Mobile: 0086-19953155515
Mobile website
Official WeChat Public Number
Links:Red Cross Society of China丨Shandong Red Cross Society丨Shandong Provincial Health Commission | Yinfeng Group| Yinfeng Biological Group
All rights reserved©Yinfeng Life Continuation Powered by www.300.cn SEO
