“Capturing” the Eighth Longevity Gene: Can Life Be Extended?
Release time:
2024-08-13
People often hope for a long life and therefore discuss how to achieve longevity through lifestyle choices such as exercising more, eating a balanced diet, maintaining a regular schedule, and keeping a healthy mindset. However, scientific research has revealed that various genes within our bodies regulate our lifespan.
Recently, research teams from Zhejiang University and the Chinese Academy of Sciences' Center for Excellence in Molecular Plant Sciences discovered a gene in the insect nuclear genome that co-evolves with mitochondria. This gene can significantly extend the lifespan of insects and nematodes. This gene, known as CG11837, influences mitochondrial morphology, and its expression level is directly related to an organism’s lifespan. Reduced expression of this gene shortens life, while increased expression extends it.
To prove this discovery, the researchers conducted experiments in which the expression of the CG11837 gene was reduced in six different animals, resulting in a significant shortening of their lifespan by up to 25%. Subsequently, they performed overexpression experiments of the gene in fruit flies and nematodes, leading to a substantial extension of their lifespan by about 12%. This indicates that activating the CG11837 gene can enhance anti-aging capabilities by 30%.
Through comparisons in the global longevity gene database, the authors found that this gene is the eighth widely recognized gene internationally that extends animal lifespan. Its discovery provides important clues for understanding the molecular mechanisms of aging and could offer new targets for delaying aging and treating age-related diseases.
In fact, it is challenging to simply define a gene in the human body as a “longevity gene.” Currently, seven genes have been confirmed by scientific literature and research to be closely associated with extending lifespan. The SIRT1 gene is believed to be related to aging and lifespan regulation. The APOE gene mainly regulates lipid metabolism. The FOXO3A gene is a mutated gene observed among centenarians of various races worldwide, with activation effects including blocking the cell division cycle, repairing DNA damage, promoting autophagy, enhancing cellular antioxidant capacity, and preventing cellular carcinogenesis. The CETP gene regulates cholesterol metabolism, increasing high-density lipoprotein cholesterol and reducing cardiovascular disease risk, thus extending lifespan. The insulin-like growth factor receptor IGF1R gene regulates human growth and metabolism, and reduces the occurrence of cancer and metabolic diseases. The KLOTHO gene has antioxidant and anti-aging effects, can improve cognitive function, and prevents cardiovascular diseases and osteoporosis. The MTOR gene regulates cell growth and protein synthesis, preventing age-related diseases.
Understanding the mechanisms of these genes might help us find the secrets to eliminating age-related diseases and extending life.
Previous article
Next article
Previous article
Next article
Latest developments
The debut and discourse of the YinFeng Life Continuation Project not only served as an authoritative demonstration of its own ethical governance framework but also contributed practical wisdom toward establishing industry norms.
Yinfeng Foundation Honored as "2025 Public Welfare Donor" by Jinan Red Cross
Looking ahead, Yinfeng Foundation will use this recognition as an opportunity to further deepen its strategic collaboration with the Jinan Red Cross, expand cooperation in areas such as life health and emergency response, and continue to empower efforts to accelerate the construction of a "new, strong, excellent, rich, beautiful, and high-quality" modern socialist strong capital city, contributing even more Yinfeng strength to this endeavor.
The team successfully developed the CryoSIM platform, an intelligent microfluidics and deep learning-integrated system. This platform deeply integrates core technologies of deep learning and microfluidics to enable high-throughput, high-precision automated analysis of oocyte membrane permeability. It provides a novel technological tool for optimizing and advancing the clinical translation of oocyte cryopreservation techniques. Additionally, it offers an innovative practical paradigm for the application of artificial intelligence in low-temperature biomedicine and reproductive medicine.
Public Welfare Partnership: A Special Letter from the Jinan Red Cross
On the afternoon of January 30, 2026, the Jinan Red Cross presented a letter of special significance to the Shandong Yinfeng Life Science Public Welfare Foundation (hereinafter referred to as the Yinfeng Foundation).
World’s First Achievement Highlights Brand Leadership
In the future, Yinfeng Life Science Research Institute will continue to uphold its mission of "Dedicated to Medical Technology, Safeguarding Human Health." It will empower brand building with more original and pioneering scientific and technological achievements, contributing wisdom and strength to Shandong's goal of building a national regional innovation hub and promoting Chinese brands on the global stage.
Global First Ovarian Tissue Dual Activation Technology Debuts at 2025 Jinan Achievements Conference
Currently, the ovarian tissue dual activation technology has been successfully applied in clinical practice at Beijing University of Chinese Medicine Shenzhen (Longgang) Hospital, having treated over 400 patients with a treatment success rate of 70%. Over the next three years, Shandong Yinfeng Life Science Research Institute plans to use Jinan as a center to gradually expand the transformation and application of this technological achievement nationwide.
Yinfeng Life Continuation Plan
Address: Yinfeng Biotechnology Park, 1758 Gangyuan 6th Road, High-tech Zone, Jinan City, Shandong Province
Zip Code: 250102
Telephone: 0086-0531-88897351
Mobile: 0086-19953155515
Mobile website
Official WeChat Public Number
Links:Red Cross Society of China丨Shandong Red Cross Society丨Shandong Provincial Health Commission | Yinfeng Group| Yinfeng Biological Group
All rights reserved©Yinfeng Life Continuation Powered by www.300.cn SEO
