Yinfeng Institute’s Ovarian Tissue Cryopreservation Technology Wins Shandong Refrigeration and Air Conditioning Science and Technology Award
Release time:
2025-05-27
Recently, the "Novel Technology for Ultra-Low Temperature Cryopreservation, Activation, and Transplantation of Human Ovarian Tissue," developed through a collaborative effort between Shandong Yinfeng Life Science Research Institute and Beijing University of Chinese Medicine Shenzhen Hospital, has been awarded the 2025 Shandong Refrigeration and Air Conditioning Science and Technology Award. This groundbreaking technology pioneers a new pathway for female fertility preservation, marking a significant leap in China’s interdisciplinary advancements in reproductive medicine and cryobiology.
The research team innovatively combined in vitro activation of primordial follicles (IVA) with cytokine extraction from autologous venous blood (PFC) to establish a safe and effective method for activating dormant follicles. This breakthrough offers personalized treatment for patients with premature ovarian insufficiency (POI) and poor ovarian response (POR), achieving the world’s first successful case of natural pregnancy in a patient with ovarian failure.
The team’s IVA technology involves extracting a small piece of ovarian cortical tissue via laparoscopic surgery, followed by low-temperature activation in vitro and subsequent in situ transplantation within approximately one hour. This process transforms atrophied ovarian tissue into a softer, rejuvenated state. Postoperative evaluations demonstrated improvements in ovarian volume, follicle count, ovarian artery blood flow, and normalized hormone levels. The technology also provides fertility preservation options for cancer patients.
This achievement, born from the ingenuity of Chinese scientists, not only brings new hope to families but also highlights China’s innovative prowess in life sciences and cryomedicine. Where cutting-edge technology meets the miracle of life, this breakthrough stands as a national milestone in humanity’s fight against fertility challenges.
Building on this recognition, Yinfeng’s cryomedicine team will collaborate with research institutions to accelerate the development of a comprehensive "cryopreservation-rewarming-transplantation" technological ecosystem, advancing the application of cryogenic technologies for human health.
Background: Launched in 2024 by the Shandong Association of Refrigeration, the Shandong Refrigeration and Air Conditioning Science and Technology Award honors individuals and organizations for innovative contributions to refrigeration and air conditioning technologies, including pioneering research, technological development, and the promotion of scientific achievements. The award has played a vital role in advancing technological progress and innovation within the province’s refrigeration and air conditioning industry.
Latest developments
Over the two days, the symposium was not only a collision of ideas but also seeds sown to advance social progress in life culture. The Shandong Yinfeng Life Science Public Welfare Foundation will continue to use technology as wings and culture as roots, collaborating with all sectors of society to enhance the quality of life for the Chinese people and build a human-centered life care system.
According to recent announcements by the Jinan Municipal Bureau of Science and Technology, 11 outstanding achievements from Jinan have been included in the 2025 "Shandong Outstanding Achievements Report" project. Among them is the globally first-of-its-kind ovarian tissue dual-activation technology developed by Shandong Silver Med Life Science Research Institute (Jinan).
Recently, Frigid Zone Medicine, an authoritative international journal in the field of cryomedicine, published an important review titled "Advances in the Detection Methods for Assessing the Viability of Cryopreserved Samples". Written by the team of Yinfeng Cryomedical Research Center, the article systematically reviews and analyzes various detection techniques currently used to evaluate the viability of cryopreserved cells, tissues, and organs. It also proposes key directions from the perspectives of methodological integration and future instrument development, offering crucial theoretical support and practical guidance for the long - term cryopreservation of complex tissues and organs.
Recently, the "Novel Technology for Ultra-Low Temperature Cryopreservation, Activation, and Transplantation of Human Ovarian Tissue," developed through a collaborative effort between Shandong Yinfeng Life Science Research Institute and Beijing University of Chinese Medicine Shenzhen Hospital, has been awarded the 2025 Shandong Refrigeration and Air Conditioning Science and Technology Award. This groundbreaking technology pioneers a new pathway for female fertility preservation, marking a significant leap in China’s interdisciplinary advancements in reproductive medicine and cryobiology.
On May 19, a delegation from the Chinese Training Workshop for Government Officials of Developing Countries visited the exhibition hall of Yinfeng Biological Group's Cryomedicine Research Center. Government officials from multiple countries gained in-depth insights into Yinfeng’s innovative achievements in cryobiomedicine, cell storage, genetic technology, and other fields. They engaged in discussions with the delegation on technology transfer and international cooperation, contributing to the building of a global community with a shared future for humanity.
Yinfeng Life Continuation Plan
Address: Yinfeng Biotechnology Park, 1758 Gangyuan 6th Road, High-tech Zone, Jinan City, Shandong Province
Zip Code: 250102
Telephone: 0086-0531-88897351
Mobile: 0086-19953155507
Mobile website
Official WeChat Public Number
Links:Red Cross Society of China丨Shandong Red Cross Society丨Shandong Provincial Health Commission | Yinfeng Group| Yinfeng Biological Group
All rights reserved©Yinfeng Life Continuation Powered by www.300.cn SEO
