Zhejiang University's Run Run Shaw Hospital Develops "Bone Glue", Revolutionizing Orthopedic Treatment
Release time:
2025-09-19
On September 9th, Run Run Shaw Hospital, affiliated with Zhejiang University's School of Medicine, announced a significant scientific achievement: the self - developed "Bone 02" bone glue for fractured bones. This innovative biomaterial can bond and fix bone fragments in the human blood environment, potentially changing traditional orthopedic treatments and reducing the use of metal implants.
Fractures are common clinical injuries, typically treated with metal implants like screws and plates. However, these methods struggle with comminuted fractures. Lin Xianfeng, a deputy chief physician at the hospital's orthopedics department, pointed out that traditional metal fixation has issues such as inaccurate anatomical reduction, time - consuming small bone - fragment fixation, and potential bone - fragment loss, which can lead to poor healing and arthritis, especially in joints.
To solve these problems, Lin's team was inspired by oysters' adhesion mechanism. They developed "Bone 02" by specially proportioning natural inorganic and organic components of the human body. This bone glue can bond strongly within 2 - 3 minutes in a blood - wet environment, is easy to use, boosting surgical efficiency. It's fully biodegradable, being absorbed about six months after bone healing, thus avoiding the pain of a second operation.
Currently, Run Run Shaw Hospital, along with other medical institutions, completed a multi - center randomized controlled clinical study on comminuted - fracture bonding treatment. "Bone 02" demonstrated good safety and efficacy in over 150 patients, meeting all preset standards.
A young worker with a comminuted wrist fracture was a case in point. The traditional treatment would involve large incisions, high risks, and a second operation. With "Bone 02", doctors used a 2 - 3 cm minimally invasive incision, completing the bonding in 3 minutes. Three - month follow - up showed excellent healing and full wrist - joint function recovery.
Lin Xianfeng said they hope patients can have fractures bonded with a simple injection in the future, shortening recovery time. The bone glue is applicable to various fractures throughout the body, especially hard - to - fix small fragments. Its quick - bonding and easy - use features also hold promise for defense, military, and disaster - rescue scenarios.
This innovation represents a major breakthrough in China's minimally invasive fracture treatment and brings new hope to global orthopedics.
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