Science is a big deal! The secret of longevity that can live 200 years has been found in the depths of the ocean.
For natural life, aging and death are inevitable. A common sign of aging is that cells slowly lose their ability to produce new healthy cells to repair damage.
However, as vertebrates, some Pacific rockfish can live more than 200 years old, while others can only live about 10 years old. The lifespan of the two is 20 times less! This makes the former one of the longest-lived vertebrates. This difference in lifespan has attracted a great deal of interest from scientists.
Recently, Science magazine revealed to us the mystery behind this longevity in the form of a cover paper.
Scientists from the University of California, Berkeley, USA collected tissue samples from 88 species of rockfish and sequenced the whole genome. The study found that the longevity group is rich in DNA repair pathway and 137genes related to longevity, which affect longevity directly by affecting insulin signal transduction and other pathways, as well as indirectly by affecting size and environmental adaptation.
We know that as organisms grow old, they accumulate DNA damage, which in turn may further accelerate the aging process. If these damaged DNA can be repaired in time, the genome can be kept in a "young state" and aging can be delayed.
The body size and lifespan of different rock fish are different.
At the same time, scientists say that if you want to live a long life, it depends on your environment. They found that larger rockfish living in the deep sea, deeper and colder waters, slowed their metabolism and were less likely to get sick from microbial infections, which were associated with longer lifespans.
The study was published in the top international academic journal Science on November 11, 2021, entitled: Origins and evolution of extreme life span in Pacific Ocean rockfishes.
Scientists hope that longevity rockfish will provide humans with strategies to improve longevity. Strategies to improve DNA repair and control inflammation may prolong life and healthy life.
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