Science Outreach-YINFENG LIFE EXTENSION PROGRAM

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A "Head-to-Head" Scientific Comparative Study: YF Cryoprotectant Self-Developed by Yinfeng Life Science Research Institute Demonstrates Significantly Superior Safety and Ice Inhibition Efficacy

Breakthrough Organ Preservation Technology: Achieving Long-Term and Safe Preservation of Cells and Organs

Breaking the Cryopreservation Bottleneck: New Pretreatment Technique Boosts NK Cell Recovery Rate to 90%–100% After Thawing

Scientists Achieve Functional "Revival" of Mouse Brain Tissue After Rewarming from -196°C Freezing First Successful Revival of Frozen Brain! Mouse brain tissue regains memory function after being frozen at -196°C and rewarmed

Good News! Three Organoid Cryopreservation Technologies of Our Team Accepted for National Patents

The World's First In - Vitro Dual Activation Technology for Primitive Follicles: A Baby Born after Intra - operative Ovarian Tissue Freeze - Thaw Transplantation

A "Head-to-Head" Scientific Comparative Study: YF Cryoprotectant Self-Developed by Yinfeng Life Science Research Institute Demonstrates Significantly Superior Safety and Ice Inhibition Efficacy

2026/09/09

This head‑to‑head comparative study, backed by solid and transparent data, unequivocally demonstrates that China‑developed cryoprotectants already possess significant international competitiveness in core performance. This not only reflects Yinfeng's technological prowess but also serves as a compelling testament to China's cryobiomedicine field transitioning from "following" to "running alongside" global leaders—earning international discourse power through scientific evidence.

Breakthrough Organ Preservation Technology: Achieving Long-Term and Safe Preservation of Cells and Organs

2026/05/18

Beyond organ transplantation, this non-toxic low-temperature preservation framework can be extended to long-term storage of stem cells, reproductive cells, and germplasm resources of endangered species, providing a universal technological foundation for biobanks, regenerative medicine, and other fields.

Breaking the Cryopreservation Bottleneck: New Pretreatment Technique Boosts NK Cell Recovery Rate to 90%–100% After Thawing

2026/04/29

The clinical value of this approach lies in its extremely simple operation. It requires no specialized cryopreservation solutions or complex equipment, using only GMP‑grade compliant cytokines that can be removed by routine washing after pretreatment, posing no additional safety risks to patients and enabling rapid integration into existing cell production and cryopreservation workflows. As the large‑scale manufacturing of NK cells derived from umbilical cord blood and iPSCs becomes increasingly mature, combining this cryopreservation technology holds the potential to significantly reduce cell therapy costs and improve accessibility, opening new avenues for immunotherapy in hematological malignancies and solid tumors.

Scientists Achieve Functional "Revival" of Mouse Brain Tissue After Rewarming from -196°C Freezing First Successful Revival of Frozen Brain! Mouse brain tissue regains memory function after being frozen at -196°C and rewarmed

2026/03/16

In science fiction, human cryopreservation and resuscitation are often regarded as a "time capsule" to the future. Now, this concept has achieved a milestone breakthrough in the laboratory—scientists have for the first time successfully cryopreserved adult mouse brain slices in liquid nitrogen at -196°C and restored multiple key neural functions, including learning and memory mechanisms, after rewarming. This achievement blazes a brand-new trail for basic neuroscience research and organ preservation technology.

Good News! Three Organoid Cryopreservation Technologies of Our Team Accepted for National Patents

2025/08/15

In the era of rapid development of organoid research, achieving long - term stable preservation while maintaining biological activity and functional integrity remains a crucial bottleneck restricting the clinical translation of this technology and its application in drug R & D. Recently, three technological inventions by the research team of Yinfeng Low - Temperature Medical Research Center were accepted by the National Intellectual Property Administration. These three technologies focus on the challenges of organoid cryopreservation and cover the key steps in the entire process of organoid vitrification preservation, offering a more efficient and reliable solution for safeguarding biological samples in organoid research.

The World's First In - Vitro Dual Activation Technology for Primitive Follicles: A Baby Born after Intra - operative Ovarian Tissue Freeze - Thaw Transplantation

2025/07/03

On June 25, 2025, the team led by Professor Wang Huiying and Dr. Jin Bo from Shenzhen Hospital of Beijing University of Chinese Medicine collaborated with Shandong Yinfeng Life Science Research Institute to develop the "ovarian dual activation" technology. Through this technology, patients with POI (primary ovarian insufficiency) underwent intra - operative freeze - thaw activation of ovarian tissue. After intra - operative transplantation, a baby was born, and both the mother and the baby are healthy and safe.

2026-11-06

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Nature Study Reveals the Molecular Mechanism by Which Mild Cold Extends Lifespan

Moderate cold exposure can extend lifespan across many species — a phenomenon observed and recorded for over a century, yet its molecular mechanism has remained unclear. Recently, a team led by David Vilchez and Christian Frezza at the University of Cologne published a study in Nature, reporting a metabolite-mediated, multi-tissue signaling pathway that links cold temperature to both lifespan extension and the maintenance of protein homeostasis.

2026-11-06

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A Human First! Gene-Editing Technology Directly Rewrites DNA Inside the Body

A powerful gene-editing technology has been used to edit DNA directly inside the human body — the first such treatment known to date. "Prime editing," a technique more precise than the conventional CRISPR-Cas9 method, is being used to rewrite DNA in liver cells to repair the gene mutation that prevents the body from expelling excess copper, treating a rare disease called Wilson disease.US biotech company Prime Medicine announced that earlier this month it successfully treated the first participant, with initial results expected next year.

2026-10-30

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Goodbye DMSO! MIT Uses "Antifreeze Sugars" to Preserve CAR-T Cells: Thaw-and-Inject, With Better Efficacy

For cryomedicine practitioners, the takeaway is this: cryopreservation is no longer just about keeping cells "alive" — it is being designed as a manufacturing step that shapes final therapeutic efficacy, which is precisely the key to whether "thaw-and-inject" can truly become reality.

2026-10-30

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World First! "Rejuvenation" Gene Injected into a Human: First Patient Says "the World Is Brighter Again"

Life Biosciences, a US biotech company, has released the latest Phase 1 clinical trial data for its cellular reprogramming therapy ER-100 — the world's first age-reversal gene therapy trial. After the "rejuvenation" gene was injected into participants' eyes, the first three open-angle glaucoma patients all tolerated it well, and two have already shown early signs of vision improvement.

2026-10-23

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Cryopreservation Breakthrough: Low-Dose Preconditioning Makes NK Cells "Fitter After Freezing"

The study forms a complete evidence chain from mechanistic dissection to intervention validation, indicating that cryopreservation is moving from an empirical craft toward precise design grounded in cell-death mechanisms. With optimization of cryoprotectant formulations, standardization of operating parameters and the development of novel preconditioning strategies, cryobiological technology will continue to provide solid support for immune cell therapy, cell bank construction and even regenerative medicine.

2026-10-23

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No Fertilization Needed: A Clump of Cells Grew a Beating Heart on Its Own

The ethical boundary is just as clear: guidelines updated in 2025 by the International Society for Stem Cell Research prohibit implanting human stem-cell embryo models into human or animal uteri, and China's Ethical Guidelines for Human Organoid Research stipulate the same. As for when the first mouse will be born, Ding Sheng can give no timetable: "It is still a scientific question, not an engineering one."

2026-10-19

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Spinning Circuit Systems Directly into Fibers! Woven Robotic Electronic Skin Becomes Possible

The results provide a new underlying technology path for the development of embodied intelligent perception, flexible human-machine interaction, and soft robotics, and are expected to promote the flexible electronics industry from single-point innovation toward systematic application.

2026-10-19

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Tardigrade Antifreeze Mechanism Achieves 89% Red Blood Cell Recovery

The American Chemical Society (ACS) recently announced that a study published in ACS Applied Materials & Interfaces applied the extreme-environment survival strategies of tardigrades (commonly known as water bears) to red blood cell cryopreservation and restored red blood cell counts in an anemic mouse model.

2026-09-24

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Light-Speed Thawing of Oocytes: 2D Material + Laser Raises Recovery Survival Rate to 81%

The path validated by this work is clear—allowing samples to rapidly and uniformly traverse the dangerous temperature zone from within to suppress devitrification, providing a useful approach for the cryopreservation of oocytes and even embryos and organs.

2026-09-24

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Brain Implant Simultaneously Decodes Speech and Gestures, Giving Paralyzed Patients a New Way to “Speak”

However, initial validation has clearly shown that a single brain implant is enough to support multifunctional natural communication, paving the way for paralyzed patients to rebuild an expressive ability that combines speech and gesture.