Science Outreach-YINFENG LIFE EXTENSION PROGRAM

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A "Head-to-Head" Scientific Comparative Study: YF Cryoprotectant Self-Developed by Yinfeng Life Science Research Institute Demonstrates Significantly Superior Safety and Ice Inhibition Efficacy

Breakthrough Organ Preservation Technology: Achieving Long-Term and Safe Preservation of Cells and Organs

Breaking the Cryopreservation Bottleneck: New Pretreatment Technique Boosts NK Cell Recovery Rate to 90%–100% After Thawing

Scientists Achieve Functional "Revival" of Mouse Brain Tissue After Rewarming from -196°C Freezing First Successful Revival of Frozen Brain! Mouse brain tissue regains memory function after being frozen at -196°C and rewarmed

Good News! Three Organoid Cryopreservation Technologies of Our Team Accepted for National Patents

The World's First In - Vitro Dual Activation Technology for Primitive Follicles: A Baby Born after Intra - operative Ovarian Tissue Freeze - Thaw Transplantation

A "Head-to-Head" Scientific Comparative Study: YF Cryoprotectant Self-Developed by Yinfeng Life Science Research Institute Demonstrates Significantly Superior Safety and Ice Inhibition Efficacy

2026/09/09

This head‑to‑head comparative study, backed by solid and transparent data, unequivocally demonstrates that China‑developed cryoprotectants already possess significant international competitiveness in core performance. This not only reflects Yinfeng's technological prowess but also serves as a compelling testament to China's cryobiomedicine field transitioning from "following" to "running alongside" global leaders—earning international discourse power through scientific evidence.

Breakthrough Organ Preservation Technology: Achieving Long-Term and Safe Preservation of Cells and Organs

2026/05/18

Beyond organ transplantation, this non-toxic low-temperature preservation framework can be extended to long-term storage of stem cells, reproductive cells, and germplasm resources of endangered species, providing a universal technological foundation for biobanks, regenerative medicine, and other fields.

Breaking the Cryopreservation Bottleneck: New Pretreatment Technique Boosts NK Cell Recovery Rate to 90%–100% After Thawing

2026/04/29

The clinical value of this approach lies in its extremely simple operation. It requires no specialized cryopreservation solutions or complex equipment, using only GMP‑grade compliant cytokines that can be removed by routine washing after pretreatment, posing no additional safety risks to patients and enabling rapid integration into existing cell production and cryopreservation workflows. As the large‑scale manufacturing of NK cells derived from umbilical cord blood and iPSCs becomes increasingly mature, combining this cryopreservation technology holds the potential to significantly reduce cell therapy costs and improve accessibility, opening new avenues for immunotherapy in hematological malignancies and solid tumors.

Scientists Achieve Functional "Revival" of Mouse Brain Tissue After Rewarming from -196°C Freezing First Successful Revival of Frozen Brain! Mouse brain tissue regains memory function after being frozen at -196°C and rewarmed

2026/03/16

In science fiction, human cryopreservation and resuscitation are often regarded as a "time capsule" to the future. Now, this concept has achieved a milestone breakthrough in the laboratory—scientists have for the first time successfully cryopreserved adult mouse brain slices in liquid nitrogen at -196°C and restored multiple key neural functions, including learning and memory mechanisms, after rewarming. This achievement blazes a brand-new trail for basic neuroscience research and organ preservation technology.

Good News! Three Organoid Cryopreservation Technologies of Our Team Accepted for National Patents

2025/08/15

In the era of rapid development of organoid research, achieving long - term stable preservation while maintaining biological activity and functional integrity remains a crucial bottleneck restricting the clinical translation of this technology and its application in drug R & D. Recently, three technological inventions by the research team of Yinfeng Low - Temperature Medical Research Center were accepted by the National Intellectual Property Administration. These three technologies focus on the challenges of organoid cryopreservation and cover the key steps in the entire process of organoid vitrification preservation, offering a more efficient and reliable solution for safeguarding biological samples in organoid research.

The World's First In - Vitro Dual Activation Technology for Primitive Follicles: A Baby Born after Intra - operative Ovarian Tissue Freeze - Thaw Transplantation

2025/07/03

On June 25, 2025, the team led by Professor Wang Huiying and Dr. Jin Bo from Shenzhen Hospital of Beijing University of Chinese Medicine collaborated with Shandong Yinfeng Life Science Research Institute to develop the "ovarian dual activation" technology. Through this technology, patients with POI (primary ovarian insufficiency) underwent intra - operative freeze - thaw activation of ovarian tissue. After intra - operative transplantation, a baby was born, and both the mother and the baby are healthy and safe.

2026-08-14

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From DMSO to AI-Driven Rational Design: Borrowing from the Drug Discovery Paradigm to Unlock the "Vitrification Dilemma" in Organ Cryopreservation

By integrating the systematic optimization framework of drug discovery with a materials-science perspective, CPA design is evolving from empirical trial-and-error toward rational innovation. As "cryo-omics" data accumulate and AI tools mature, safer and more effective cryoprotectants and formulations are poised to emerge at an accelerated pace—paving the way for the long-term preservation of human cells, tissues, and ultimately whole organs.

2026-08-10

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A Paradigm-Shifting Breakthrough: The "Cryo-Stasis" Framework Enables Low-Toxicity Vitrification of Small-Diameter Arterial Grafts

" It extends evaluation endpoints to nuclear envelope stability, tissue viscoelasticity, and post-transplant functionality. This work establishes a quantifiable experimental paradigm and a new technical starting point for the low-toxicity vitrification of viable vascular and complex tissues.

2026-07-17

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Landmark Breakthrough in Bioengineered Kidneys: High-Fidelity Renal Organoids Advance Toward Clinical Translation

While the journey from microscopic lab-grown organoids to transplantable, fully functional kidneys remains long, this study has undoubtedly unlocked a critical gateway to harnessing the “magic of development,” kindling new hope for millions of patients worldwide.

2026-07-17

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Unlocking the Code of Hematopoietic Aging: Scientists Identify Novel Target to Reverse Immune Decline

This study not only elucidates a novel mechanism underlying hematopoietic aging but also offers promising new targets and therapeutic strategies for addressing age-related immunodeficiency, chronic inflammatory diseases, and even systemic aging itself. Looking ahead, precise modulation of this pathway may become a powerful tool for slowing the aging process and revitalizing the immune system.

2026-07-10

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Lab-Grown "Potato Cells": A Milestone in Building Life from Scratch

From "simulating life" to "creating it," humanity has journeyed for decades. SpudCell may not be the final destination, but the spark it ignites is illuminating a new path for synthetic biology toward real-world utility.

2026-07-10

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Healing Without Snipping DNA: Epigenetic Editing Opens a New Frontier in Gene Therapy

This "revolution without scissors" is nevertheless opening up vast new possibilities for the future of gene therapy.

2026-06-26

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Cover Story | Solving the Challenge of Deep Hypothermic Brain Protection: Unveiling a Novel Mechanism of White Matter Injury

This study not only fills a critical mechanistic gap in the field of hypothermic brain protection but also provides precise therapeutic targets for the prevention and treatment of white matter injury after complex congenital heart surgery.

2026-06-26

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《Science》: Hyaluronic Acid and Tissue Mechanics Synergistically Regulate Mammalian Digit Tip Regeneration

This work was completed by scholars including Mui, Wong, and Storer from the University of Cambridge. In the same issue, Science also published a related study on oxygen-sensing regulation of limb regeneration, collectively providing important breakthroughs in understanding the mechanisms of mammalian regeneration.

2026-06-22

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Novel Strategy for Cell Cryopreservation: Pre-Dehydration via Droplet Vacuum Evaporation

This approach holds broad application prospects in regenerative medicine (e.g., stem cell transplantation and organoid transplantation), drug screening (preservation of high‑throughput cell models), and biobanking (long‑term storage of rare cell resources).

2026-06-22

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Cell Cover: Atlas of Human Cellular Senescence Unveiled, Ushering in the Era of Precision Anti-Aging

Professor Rong Fan, Executive Director of the SenNet consortium, remarked: “This atlas allows us, for the first time, to see the true distribution and diversity of senescent cells within the human body.” The consortium has made all data openly accessible at https://data.sennetconsortium.org for researchers worldwide. Industry experts believe this achievement will shift the medical paradigm from “treating disease after onset” to “pre‑identifying and eliminating harmful senescent cells,” with promising breakthroughs expected in neurodegenerative diseases, fibrotic liver disease, chronic wounds, and metabolic syndrome.