World's first! "Pig liver" successfully transplanted into the human body


On March 10, led by Academician Dou Kefeng of the Chinese Academy of Sciences and Director Tao Kaishan from Hepatological Surgery Department, Xijing Hospital of Air Force Military Medical University made a major breakthrough in the clinical research of liver heterotransplantation: the whole liver of a multi-gene edited pig was successfully transplanted into a brain-dead patient using the auxiliary liver transplantation method. During the operation, the transplanted liver secreted bile immediately after blood flow was restored with no hyperacute rejection, and functioned continuously for more than 96 hours.

Heavyweight! Prof. Gang Zhao, the main committee member of Yinfeng Cryomedicine Specialized Committee, published another article "Advanced Cryopreservation Engineering Strategies - A Critical Step in Utilizing Stem Cell Products".


Cryopreservation is known as the technique of solidifying time, by cooling biological materials (e.g. cells, tissues and organs) to low temperatures with the addition of cryoprotectants (generally -196°C liquid nitrogen preservation), and then rewarming them to normal temperatures (37°C) in an effective manner when needed, at which time the biological samples can still be restored and maintain their activity.

Heavy! Professor Zhao Gang, chairman of our special committee, jointly published an important article - "Principles and Progress of Cell Cryopreservation"


In recent years, low-temperature biomedicine, a less popular subject, is attracting more and more attention, attracting more and more scientists to join it. Among them, the cryopreservation technology of cells, tissues and organs, and even the entire human body continues to make progress and is gradually used in clinical applications.

Science's latest cover article: Vital organs resuscitated after cryogenic freezing


On June 30, 2023, Science Magazine published the article "Frozen in time" by Warren Cornwall, detailing the first successful transplantation of vitrified-preserved and nanoheated rat kidneys by Professor John Bischof's team at the University of Minnesota (UMN). . As the most exciting research in the field of cryopreservation of tissues and organs, this article successfully appeared on the cover of Science, Volume 380, Issue 6652.


Breaking! U.S. transplants pig kidneys to humans, now surviving for over a month

As we all know, organ transplantation, as the last resort treatment for many end-stage organ diseases, has long been in an objective situation where demand far exceeds supply (organ donation). As a result, many research teams have also put their hopes for a breakthrough in the field of xenotransplantation - trying to make pig hearts, pig kidneys and pig livers work in the human body.


Spinal cord-like tissue transplantation helps paralyzed rats regain motor function

Dai Jianwu, a researcher at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (IGDB, CAS), and Yannan Zhao, a young researcher, have made a new progress in the study of in vitro fabrication of human spinal cord tissues, which, when transplanted, help to restore motor functions in paralyzed rats. The related study was recently published in Science Advances.


The real-life version of "Avatar" is here! Scientists create human organs with chips

In medical research laboratories, we often see small animals such as mice, rabbits or frogs, which are used as animal models to become experimental, drug-testing or even anatomical objects, and make great sacrifices for human medical research.


Going beyond sci-fi: the human 4S store that makes organ repair possible

When the car traveled to a certain mileage, we need to go to the 4S store to do maintenance to the car, so as to keep the car in a safe state of use. In fact, people and cars are similar, the human body in the process of operation also need maintenance, regenerative medicine "human 4S store", through advanced regenerative medicine technology, to achieve the goal of "where the bad repair where".


Human cryopreservation: the "Everest" of cryonics

Borges, a well-known writer in the 20th century, once said that the essence of human existence is the experience of death over and over again, and "death makes people wise and sad". Therefore, in the history of mankind, people are constantly breaking through themselves, challenging the boundaries of science and technology, the peak of medicine, and the length of human life is constantly extended in the long river of time.


New Breakthroughs! New explorations in skin cryopreservation to help new advances in cryogenic research

The human body is an organic organism composed of cells and complex tissues and organs. When the tissues and organs in the body are damaged or lose their original functions, tissue and organ transplantation can replace the damaged or dysfunctional parts by implanting a part of the tissues and organs from the own body or other individuals.


Boy, 12, hit in car accident, has his head reattached and is now walking on his own.

Suleiman Hassan, a 12-year-old boy from Palestine, had his head "severed" in a car accident that separated the base of his skull from the top of his spine, but the skin was still attached, the Daily Mail and Israel Hayom reported on July 14th. His head was reattached by a group of Israeli doctors after a difficult operation. One month after the operation, the boy is now walking on his own.


Failure is the mother of success! The world's first pig heart-to-human transplant experience brings us one step closer to success

The death of the world's first pig heart transplant recipient is extremely regrettable, and people are full of questions about the cause of his death. According to a report on the University of Maryland website on June 30, the famous medical journal "The Lancet" published a study that revealed the possible reasons for the failure of the world's first genetically modified pig heart transplant.


Sleeping in the frozen soil for 46,000 years! This creature was resurrected by scientists

According to a paper in the latest issue of PLoS Genetics, a small group of nematodes taken from Siberian permafrost "came back to life" after being thawed, and although they only continued to survive for less than a month, they reproduced More than 100 generations of new nematodes were produced. These nematodes are about 46,000 years old, the same age as the woolly mammoth.


Is it possible to realize the human hibernation technology in "The Three-Body Problem" and "The Wandering Earth 2"?

"The Wandering Earth 2" is a hit, and when it comes to The Wandering Earth, we have to mention "The Three-Body Problem", which won the Hugo Award. Not long ago, the TV series "The Three-Body Problem" represented Chinese science fiction going abroad. In just a few months, it received a high score of 8.0 on IMDB. We have to say that "The Three-Body Problem" is a very good TV series.